Proton pump inhibitors in prevention of low-dose aspirin-associated upper gastrointestinal injuries
نویسندگان
چکیده
منابع مشابه
SECONDARY PREVENTION OF UPPER GASTROINTESTINAL BLEEDING IN LOW DOSE ASPIRIN USERS INFECTED WITHHELICOBACTER PYLORI
ABSTRACT Background: Aspirin even at low dose ( 100 mg) can increase the risk of upper gastrointestinal bleeding. It is usual to use low dose aspirin for cardiovascular prophylaxis. We hypothesized that Helicobacter pylori eradication is as effective as omeprazole maintenance therapy for secondary prevention of bleeding in those who take low dose aspirin and are positive for Helicobacter pylor...
متن کاملRisk management of risk management: Combining proton pump inhibitors with low-dose aspirin
Low-dose aspirin is widely used in the primary and secondary prevention of cardiovascular events, but is associated with a range of upper gastrointestinal side effects. In this review, we summarize the rationale for low-dose aspirin therapy, quantify the risk for upper gastrointestinal side effects, identify the risk factors involved, and provide an overview of preventive strategies, thereby fo...
متن کاملLow-Dose Aspirin-Induced Upper Gastrointestinal Injury-Epidemiology,Management and Prevention
Tzung-Jiun Tsai1,2 and Ping-I Hsu1,2* 1Department of Internal Medicine, Division of Gastroenterology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan 2National Yang-Ming University, Taipei, Taiwan *Corresponding author: Ping-I Hsu, Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, 386 Ta Chung 1st Road, Kaohsiung 813, Taiwan, Tel: +886-7-...
متن کاملSuboptimal prescribing of proton-pump inhibitors in low-dose aspirin users: a cohort study in primary care
OBJECTIVE Determine the adherence to recommendations of concomitant proton-pump inhibitor (PPI) treatment in regular low-dose of aspirin (LDASA) users, taking factors associated with the probability of receiving a PPI into account. DESIGN Cohort study. SETTING Data were obtained from 120 Dutch primary care centres participating in the Netherlands Information Network of Primary Care (LINH). ...
متن کاملCost-effectiveness of proton pump inhibitor cotherapy in patients taking long-term, low-dose aspirin for secondary cardiovascular prevention.
BACKGROUND Patients with coronary heart disease (CHD) require long-term therapy with low-dose aspirin (ASA). Although these patients are at increased risk for upper gastrointestinal bleeding (UGIB) and proton pump inhibitor (PPI) cotherapy may reduce such risk, it is not known whether lifelong PPI cotherapy is cost-effective. METHODS A Markov model was developed to compare lifelong therapy wi...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2015
ISSN: 1007-9327
DOI: 10.3748/wjg.v21.i17.5382